Candide

roman catholic by birth; scientific atheist by choice; sinner by merit. blogging on brains, evolution and language. gaidhlig-speaking neuroscience student at oxford. likes to Question Everything!

Little Microbiology Blog: BBC Horizon: Defeating the Superbugs

littlemicrobiologyblog:

Ok so I should have told you all about this show last night before it was aired, but I recorded it myself so didn’t think about it, sorry! (If you didn’t watch it and want to then it’s on iPlayer here: http://www.bbc.co.uk/iplayer/episode/b01ms5c6/Horizon_20122013_Defeating_the_Superbugs/)

The episode deals with the pressing issue of resistance of bacteria to many clinical antibiotics due to our actions in the use of these compounds.

Reblogging because I enjoyed this program and suggest my followers watch it. What I found especially fascinating was this Harvard researcher who had set up a petri ‘table’ for growing e-coli. As you went along the table, the concentration of an antibiotic was increased. The bacteria were added at the end with no antibiotic, and slowly colonized up the concentration gradient. By the time you got to the end of the table, the antibiotic concentration had increased a thousandfold and the bacteria growing there were of course highly resistant to the antiobiotic. In this way, in less than a fortnight the researchers managed to create a strain of superbug bacteria by simply exposing them to the selective pressure of increasingly concentrated antiobiotics. When you think about it, that’s pretty bloody terrifying!

8 months ago - 6

Peace In Our Time: Steven Pinker’s The Better Angels Of Our Nature - A Review (for the lolz)

Predictions of perpetual peace are the highlight of any history of hubris. Chamberlain is classic and quotable. The various Paxes (from Austrialana in New Guinea to Romana in Europe) are inevitably followed by a decline and fall. Francis Fukuyama famously prophesized the end of history and the triumph of a pacific liberalism – only for his tower to topple with the return of ideological violence in the form of 9/11.

Steven Pinker, however, is clever than that. The Harvard professor – psycholinguist by training, public intellectual by trade – is careful to avoid playing the futurist. The Better Angels Of Our Nature finds it surprises in the past instead, with Pinker working hard to prove to us that violence has in fact declined, using some three score graphs and hundreds of pages of analysis. Marshalling together the datasets of obscure criminologists and military historians, he ably demonstrates that homicide rates, battle casualty rates, execution rates, abuse rates and hate crime rates have all fallen over the last millennium.

Pinker believes we have been conditioned to believe that these are indeed the worst of times – school history consists of little more than World War Two and the Holocaust; TV shows like Law & Order meet rapists and serial killers every week; and the news media obsesses over civil wars and psychopaths. But was the 20th century really the most violent in history? The absolute figures speak of 50 million deaths in WW2, including six million victims of Nazi genocide. Nonetheless for Pinker – a secular Jew – this body count is too simplistic an analysis. The numbers may horrify but what do they really say about how violent the century was?

The thesis of the book depends on using proportions rather than plain figures. For instance, archaeology and anthropology have revealed that pre-state societies often kill up to 15% of their people in war, while the figure for the entire 20th century is just 3%! The decline is very real: for homicide, we have up to 300 deaths per 100,000 in pastoral tribes, then 50 per 100,000 in medieval England, and 8 per 100,000 for the planet today, which to falls to just 1 per 100,000 in Europe. By using rates instead of absolute numbers we get a nice figure for how likely it is a particular person will die a violent death in a given society.

Yet from a God’s eye perspective six million deaths is clearly worse than six. It seems crass and offensive, for example, to suggest the Holocaust is a lesser tragedy than a raid in New Guinea. But compare six million murders in a population of one billion to six in a population of a hundred. From my perspective, I’m ten times as likely to die in the second society – I’d have a better chance of surviving the genocide than the raid!

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zachstone:

Hilary Term by iPhone. From my walks to and from town this HT. The nice thing about the commute is the oppertunity to savor how Oxford looks in all kinds of light and weather. 

As I am on Tumblr instead of revising, I thought I’d reblog this motivational imagery to make me work harder to make sure I actually manage to achieve my conditions…

I am sure we will all be hearing about Domhnall Iain MacDonald in the years to come. His academic ability is matched by the genuinely inquisitive intellect of a polymath.

My Physics Teacher. I know it’s vain to post this, but its one of the coolest things anyone’s ever said about me. This guy doesn’t give praise easily, and I’m happy cos probably the only trait in my rather arrogant personality that I actually like, and am proud of, is my curiosity about the world. 

Suppose that every memory, written word, and piece of technology on earth was destroyed all at once, leaving humanity to start completely from scratch. Everything we have come to know about science would eventually be discovered again. Given a few thousand years, people would figure out chemistry, and rediscover all of the same elements we know about now. people would once again understand biology, including its evolutionary origins. People would eventually see the motions of other galaxies in the sky, and work out the details of the big bang. This is the glorious part about science, it can and would all be replicated. I can assure you, however, that your story about a talking snake would be gone forever.

Unknown

I just want to do something worth recognition

Don’t we all!? 

I agree with the sentiment but I’d rewrite it “I just want to do something worthwhile!”

(Source: letsfallbackinlove)

tartantambourine:

““For the Scots, this is going to be decided 80 percent from the heart and 20 percent from the mind. I tell ye, I’m not the kind to wear a kilt at weddings, but I am Scottish before I am British. and I know a good many of us want our rightful independence back.””

Alistair Hunter, a 54-year-old Scottish nationalist working for the city of Edinburgh, commenting on Scotland’s drive to re-establish its independence, in “Scotland Moves Toward Vote on Independence.”

I’m voting YES just to see what happens!

Krauss is a great speaker.

Confession. The first time I read Northern Lights (The Golden Compass) it took me til Lyra’s going to London to realize that this wasn’t the real Oxford after all. I was very very young, and wonderstruck by this magical university where everyone got to have their own talking animal. So I decided I was gonna go there!

Confession. The first time I read Northern Lights (The Golden Compass) it took me til Lyra’s going to London to realize that this wasn’t the real Oxford after all. I was very very young, and wonderstruck by this magical university where everyone got to have their own talking animal. So I decided I was gonna go there!

There is a war coming, boy. The greatest war there ever was. Something like it happened before, and this time the right side must win. We’ve had nothing but lies and propaganda and cruelty and deceit for all the thousands of years of human history. It’s time we started again, but properly this time….

John Parry to Will, The Subtle Knife, Philip Pullman